Entamoeba Histolytica How Easy is This to Detect
journal article
The Journal of Parasitology
, pp. 530-532 (3 pages)
Published By: Allen Press
https://www. jstor .org/stable/40059042
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Entameoba histolytica, 1 of the 2 Entamoeba species with similar morphology that infect humans, causes invasive intestinal and extraintestinal diseases, whereas Entamoeba dispar is found commensally and is noninvasive. Because of their morphologic similarity, E. histolytica and E. dispar cannot be differentiated microscopically. The antigens of E. histolytica and E. dispar, however, may be detected by the ELISA method. Previous studies have found that the detection of antigens in the stool is as sensitive and specific as cultures and isoenzyme analyses. Stool samples from 272 patients with diarrhea in the province of Mersin, Turkey, were examined for the presence of Entamoeba species microscopically and for Entamoeba (E. histolytical E. dispar) antigens using the ELISA method. An E. histolytica-specific ELISA test was used to examine 29 E. histolytical E. dispar-positive samples. Twenty-four (8.82%) of the samples tested positive for E. histolytical E. dispar by trichrome staining, and 29 (10.6%) of the samples tested positive for E. histolytical E. dispar by the Entamoeba screening test. Entamoeba histolytica was positive in 21 (7.72%) and E. dispar positive in 8 (2.94%) samples. The detection of true E. histolytica infection is possible with the use of E. histolytical specific antigen ELISA tests. Thus, real cases of amoebiasis can be detected and treated, and overtreatment of the patients with E. dispar, which is the nonpathogenic species, will be prevented.
The Journal of Parasitology is the official publication of the American Society of Parasitologists (ASP). It has been in print continuously since 1914, when it was founded by Henry Baldwin Ward. The journal focuses on general parasitology, as well as parasites of medical, veterinary, and economic importance. Most of the emphasis rests with eukaryotic parasites, although vectors for prokaryotic organisms and viruses are also included. The journal is printed at Allen Press in Lawrence, Kansas, in six issues per year. Institutional subscriptions are available. Membership in ASP includes receipt of the Journal of Parasitology, a quarterly Newsletter, and abstracts for the annual meetings; students can join at a much reduced rate. The journal is online via BioOne. The editor of the journal is Dr. Michael V.K. Sukhdeo. For further information regarding publication in the journal, contact the editorial office at journalofparasitology@gmail.com. For information about membership in ASP, contact the society:, http://amsocparasit.org/. For subscription information, contact asp@allenpress.com.
Allen Press plays a vital role in the dissemination of knowledge and information by partnering with organizations in the scientific, technical and medical community to promote their interests and achieve their goals. Headquartered in Lawrence, KS, Allen Press provides a comprehensive portfolio of integrated services in the broad areas of content management, online and print delivery, association management, and publishing services. Allen Press is a trusted partner of scholarly societies, professional associations and corporations nationwide.
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The Journal of Parasitology © 2008 The American Society of Parasitologists
Source: https://www.jstor.org/stable/40059042
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